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Transmembrane anion transport promoted by thioamides

Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.

Detalles Bibliográficos
Autores principales: Pomorski, Robert, García-Valverde, María, Quesada, Roberto, Chmielewski, Michał J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697034/
https://www.ncbi.nlm.nih.gov/pubmed/35423746
http://dx.doi.org/10.1039/d1ra01646f
Descripción
Sumario:Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.