Cargando…

Transmembrane anion transport promoted by thioamides

Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.

Detalles Bibliográficos
Autores principales: Pomorski, Robert, García-Valverde, María, Quesada, Roberto, Chmielewski, Michał J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697034/
https://www.ncbi.nlm.nih.gov/pubmed/35423746
http://dx.doi.org/10.1039/d1ra01646f
_version_ 1784619955004637184
author Pomorski, Robert
García-Valverde, María
Quesada, Roberto
Chmielewski, Michał J.
author_facet Pomorski, Robert
García-Valverde, María
Quesada, Roberto
Chmielewski, Michał J.
author_sort Pomorski, Robert
collection PubMed
description Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.
format Online
Article
Text
id pubmed-8697034
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-86970342022-04-13 Transmembrane anion transport promoted by thioamides Pomorski, Robert García-Valverde, María Quesada, Roberto Chmielewski, Michał J. RSC Adv Chemistry Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated. The Royal Society of Chemistry 2021-03-26 /pmc/articles/PMC8697034/ /pubmed/35423746 http://dx.doi.org/10.1039/d1ra01646f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Pomorski, Robert
García-Valverde, María
Quesada, Roberto
Chmielewski, Michał J.
Transmembrane anion transport promoted by thioamides
title Transmembrane anion transport promoted by thioamides
title_full Transmembrane anion transport promoted by thioamides
title_fullStr Transmembrane anion transport promoted by thioamides
title_full_unstemmed Transmembrane anion transport promoted by thioamides
title_short Transmembrane anion transport promoted by thioamides
title_sort transmembrane anion transport promoted by thioamides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697034/
https://www.ncbi.nlm.nih.gov/pubmed/35423746
http://dx.doi.org/10.1039/d1ra01646f
work_keys_str_mv AT pomorskirobert transmembraneaniontransportpromotedbythioamides
AT garciavalverdemaria transmembraneaniontransportpromotedbythioamides
AT quesadaroberto transmembraneaniontransportpromotedbythioamides
AT chmielewskimichałj transmembraneaniontransportpromotedbythioamides