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Transmembrane anion transport promoted by thioamides
Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated.
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697034/ https://www.ncbi.nlm.nih.gov/pubmed/35423746 http://dx.doi.org/10.1039/d1ra01646f |
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author | Pomorski, Robert García-Valverde, María Quesada, Roberto Chmielewski, Michał J. |
author_facet | Pomorski, Robert García-Valverde, María Quesada, Roberto Chmielewski, Michał J. |
author_sort | Pomorski, Robert |
collection | PubMed |
description | Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated. |
format | Online Article Text |
id | pubmed-8697034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-86970342022-04-13 Transmembrane anion transport promoted by thioamides Pomorski, Robert García-Valverde, María Quesada, Roberto Chmielewski, Michał J. RSC Adv Chemistry Thioamide groups represent useful hydrogen-bonding motifs for the development of active transmembrane anion transporters. Using a 1,8-di(thioamido)carbazole scaffold the superior performance of thioamides compared with the parent amides has been demonstrated. The Royal Society of Chemistry 2021-03-26 /pmc/articles/PMC8697034/ /pubmed/35423746 http://dx.doi.org/10.1039/d1ra01646f Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Pomorski, Robert García-Valverde, María Quesada, Roberto Chmielewski, Michał J. Transmembrane anion transport promoted by thioamides |
title | Transmembrane anion transport promoted by thioamides |
title_full | Transmembrane anion transport promoted by thioamides |
title_fullStr | Transmembrane anion transport promoted by thioamides |
title_full_unstemmed | Transmembrane anion transport promoted by thioamides |
title_short | Transmembrane anion transport promoted by thioamides |
title_sort | transmembrane anion transport promoted by thioamides |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697034/ https://www.ncbi.nlm.nih.gov/pubmed/35423746 http://dx.doi.org/10.1039/d1ra01646f |
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