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N-Alkylation/aldol reaction of α-aldimino thioesters: a facile three-component coupling reaction
Theoretical calculation of the reactivity of α-imino thioesters indicates that they are very reactive substrates for Umpolung N-alkylation. In fact, treatment of α-aldimino thioesters with dialkylzinc reagents in the presence of aldehydes or imines gives three-component coupling products in good yie...
Autores principales: | Shimizu, Makoto, Higashino, Asako, Mizota, Isao, Zhu, Yusong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697212/ https://www.ncbi.nlm.nih.gov/pubmed/35423863 http://dx.doi.org/10.1039/d1ra02000e |
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