An ionic liquid–molecularly imprinted composite based on graphene oxide for the specific recognition and extraction of cancer antigen 153

Molecularly imprinted polymers with graphene oxide (GO) as a carrier (GMIPs) were synthesized to selectively recognize and capture cancer antigen 153 (CA153). The results show that the MIP has good selectivity and adsorption for CA153, and has strong anti-interference ability. Molecularly imprinted...

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Detalles Bibliográficos
Autores principales: Han, Shuang, Yao, Aixin, Wang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697238/
https://www.ncbi.nlm.nih.gov/pubmed/35423893
http://dx.doi.org/10.1039/d1ra00134e
Descripción
Sumario:Molecularly imprinted polymers with graphene oxide (GO) as a carrier (GMIPs) were synthesized to selectively recognize and capture cancer antigen 153 (CA153). The results show that the MIP has good selectivity and adsorption for CA153, and has strong anti-interference ability. Molecularly imprinted solid phase extraction (MISPE) combined with ultra performance liquid chromatography (UPLC) for the specific adsorption of CA153 was also established, and showed great potential for the analysis of CA153 in clinics in the future.

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