Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone

A rhodium-catalyzed, N–H free indole directed cyclization reaction of benzoquinone via a dual C–H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Qijing, Li, Qianrong, Wang, Chengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697334/
https://www.ncbi.nlm.nih.gov/pubmed/35423833
http://dx.doi.org/10.1039/d1ra01779a
_version_ 1784620024681463808
author Zhang, Qijing
Li, Qianrong
Wang, Chengming
author_facet Zhang, Qijing
Li, Qianrong
Wang, Chengming
author_sort Zhang, Qijing
collection PubMed
description A rhodium-catalyzed, N–H free indole directed cyclization reaction of benzoquinone via a dual C–H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation.
format Online
Article
Text
id pubmed-8697334
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-86973342022-04-13 Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone Zhang, Qijing Li, Qianrong Wang, Chengming RSC Adv Chemistry A rhodium-catalyzed, N–H free indole directed cyclization reaction of benzoquinone via a dual C–H activation strategy is disclosed. This protocol has a good functional group tolerance and affords useful indole-fused heterocylces. Besides, it is insensitive to moisture, commercially available solvent can be directly used and work quite well for this transformation. The Royal Society of Chemistry 2021-04-07 /pmc/articles/PMC8697334/ /pubmed/35423833 http://dx.doi.org/10.1039/d1ra01779a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Zhang, Qijing
Li, Qianrong
Wang, Chengming
Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title_full Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title_fullStr Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title_full_unstemmed Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title_short Dual C–H activation: Rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
title_sort dual c–h activation: rh(iii)-catalyzed cascade π-extended annulation of 2-arylindole with benzoquinone
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697334/
https://www.ncbi.nlm.nih.gov/pubmed/35423833
http://dx.doi.org/10.1039/d1ra01779a
work_keys_str_mv AT zhangqijing dualchactivationrhiiicatalyzedcascadepextendedannulationof2arylindolewithbenzoquinone
AT liqianrong dualchactivationrhiiicatalyzedcascadepextendedannulationof2arylindolewithbenzoquinone
AT wangchengming dualchactivationrhiiicatalyzedcascadepextendedannulationof2arylindolewithbenzoquinone

Ejemplares similares