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RhANP attenuates endotoxin-derived cognitive dysfunction through subdiaphragmatic vagus nerve-mediated gut microbiota–brain axis

BACKGROUND: Atrial natriuretic peptide (ANP) secreted from atrial myocytes is shown to possess anti-inflammatory, anti-oxidant and immunomodulatory effects. The aim of this study is to assess the effect of ANP on bacterial lipopolysaccharide (LPS)-induced endotoxemia-derived neuroinflammation and co...

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Detalles Bibliográficos
Autores principales: Wu, Yuming, Zhang, Yujing, Xie, Bing, Abdelgawad, Amro, Chen, Xiaoyan, Han, Mengqi, Shang, You, Yuan, Shiying, Zhang, Jiancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697447/
https://www.ncbi.nlm.nih.gov/pubmed/34949194
http://dx.doi.org/10.1186/s12974-021-02356-z