Associations between DNA methylation and BMI vary by metabolic health status: a potential link to disparate cardiovascular outcomes

BACKGROUND: Body mass index (BMI), a well-known risk factor for poor cardiovascular outcomes, is associated with differential DNA methylation (DNAm). Similarly, metabolic health has also been associated with changes in DNAm. It is unclear how overall metabolic health outside of BMI may modify the re...

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Detalles Bibliográficos
Autores principales: Do, Whitney L., Nguyen, Steve, Yao, Jie, Guo, Xiuqing, Whitsel, Eric A., Demerath, Ellen, Rotter, Jerome I., Rich, Stephen S., Lange, Leslie, Ding, Jingzhong, Van Den Berg, David, Liu, Yongmei, Justice, Anne E., Guan, Weihua, Horvath, Steve, Assimes, Themistocles L., Bhatti, Parveen, Jordahl, Kristina, Shadyab, Aladdin, Valencia, Celina I., Stein, Aryeh D., Smith, Alicia, Staimez, Lisa R., Conneely, Karen, Narayan, K. M. Venkat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697469/
https://www.ncbi.nlm.nih.gov/pubmed/34937574
http://dx.doi.org/10.1186/s13148-021-01194-3

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