Cargando…
Recent approaches in the organocatalytic synthesis of pyrroles
Organocatalysis has emerged as one of the most important tools for the synthesis of diverse structural scaffolds, and has become one of the most important hot topics of current research. Construction of the pyrrole ring has gained much attention from the last few decades due to its remarkable biolog...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697526/ https://www.ncbi.nlm.nih.gov/pubmed/35423869 http://dx.doi.org/10.1039/d1ra01690c |
_version_ | 1784620065110360064 |
---|---|
author | Borah, Biplob Dwivedi, Kartikey Dhar Chowhan, L. Raju |
author_facet | Borah, Biplob Dwivedi, Kartikey Dhar Chowhan, L. Raju |
author_sort | Borah, Biplob |
collection | PubMed |
description | Organocatalysis has emerged as one of the most important tools for the synthesis of diverse structural scaffolds, and has become one of the most important hot topics of current research. Construction of the pyrrole ring has gained much attention from the last few decades due to its remarkable biological activities, pharmaceutical application, intermediate in the synthesis of many natural products, and material science application. With access to these 5-membered aza heterocycles, organocatalytic approaches have provided a new alternative from the perspective of synthetic efficiency, as well as from the green chemistry point of view, and a vast array of synthetic procedures has been developed. Enlightened by the significance of this growing research area, we aim to describe the recent organocatalytic approaches developed for the construction of pyrroles, and organized them based on substrates employed. |
format | Online Article Text |
id | pubmed-8697526 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-86975262022-04-13 Recent approaches in the organocatalytic synthesis of pyrroles Borah, Biplob Dwivedi, Kartikey Dhar Chowhan, L. Raju RSC Adv Chemistry Organocatalysis has emerged as one of the most important tools for the synthesis of diverse structural scaffolds, and has become one of the most important hot topics of current research. Construction of the pyrrole ring has gained much attention from the last few decades due to its remarkable biological activities, pharmaceutical application, intermediate in the synthesis of many natural products, and material science application. With access to these 5-membered aza heterocycles, organocatalytic approaches have provided a new alternative from the perspective of synthetic efficiency, as well as from the green chemistry point of view, and a vast array of synthetic procedures has been developed. Enlightened by the significance of this growing research area, we aim to describe the recent organocatalytic approaches developed for the construction of pyrroles, and organized them based on substrates employed. The Royal Society of Chemistry 2021-04-13 /pmc/articles/PMC8697526/ /pubmed/35423869 http://dx.doi.org/10.1039/d1ra01690c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Chemistry Borah, Biplob Dwivedi, Kartikey Dhar Chowhan, L. Raju Recent approaches in the organocatalytic synthesis of pyrroles |
title | Recent approaches in the organocatalytic synthesis of pyrroles |
title_full | Recent approaches in the organocatalytic synthesis of pyrroles |
title_fullStr | Recent approaches in the organocatalytic synthesis of pyrroles |
title_full_unstemmed | Recent approaches in the organocatalytic synthesis of pyrroles |
title_short | Recent approaches in the organocatalytic synthesis of pyrroles |
title_sort | recent approaches in the organocatalytic synthesis of pyrroles |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697526/ https://www.ncbi.nlm.nih.gov/pubmed/35423869 http://dx.doi.org/10.1039/d1ra01690c |
work_keys_str_mv | AT borahbiplob recentapproachesintheorganocatalyticsynthesisofpyrroles AT dwivedikartikeydhar recentapproachesintheorganocatalyticsynthesisofpyrroles AT chowhanlraju recentapproachesintheorganocatalyticsynthesisofpyrroles |