Choosing the Right Tool for Genetic Engineering: Clinical Lessons from Chimeric Antigen Receptor-T Cells

T cell modification with genes that encode chimeric antigen receptors (CAR-T cells) has shown tremendous promise for the treatment of B cell malignancies. The successful translation of CAR-T cell therapy to other tumor types, including solid tumors, is the next big challenge. As the field advances f...

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Detalles Bibliográficos
Autores principales: Irving, Melita, Lanitis, Evripidis, Migliorini, Denis, Ivics, Zoltán, Guedan, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697565/
https://www.ncbi.nlm.nih.gov/pubmed/34662233
http://dx.doi.org/10.1089/hum.2021.173

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