Cargando…

Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron−Sulfur Cluster Biogenesis Deficit

Aims: Current treatment options for ovarian clear cell carcinoma (OCCC) are limited to combination of platinum-based and other cytotoxic agents to which patients respond poorly due to intrinsic chemoresistance. There is therefore an urgent need to develop alternative therapeutic strategies for OCCC....

Descripción completa

Detalles Bibliográficos
Autores principales: Novera, Wisna, Lee, Zheng-Wei, Nin, Dawn Sijin, Dai, Melvin Zi-Yu, Binte Idres, Shabana, Wu, Hui, Damen, J. Mirjam A., Tan, Tuan Zea, Sim, Arthur Yi Loong, Long, Yun Chau, Wu, Wei, Huang, Ruby Yun-Ju, Deng, Lih-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697566/
https://www.ncbi.nlm.nih.gov/pubmed/32336105
http://dx.doi.org/10.1089/ars.2019.7850