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Stressed-out yeast do not pass GO

Using microfluidics and imaging, Argüello-Miranda et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202103171) monitor the response of individual yeast cells to nutrient withdrawal. They discover that cells arrest not only in the early G1 phase as expected, but also later in the cell cycle, an...

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Detalles Bibliográficos
Autor principal: Coller, Hilary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697686/
https://www.ncbi.nlm.nih.gov/pubmed/34932069
http://dx.doi.org/10.1083/jcb.202111032
Descripción
Sumario:Using microfluidics and imaging, Argüello-Miranda et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202103171) monitor the response of individual yeast cells to nutrient withdrawal. They discover that cells arrest not only in the early G1 phase as expected, but also later in the cell cycle, and that Xbp1 is critical for arrest at other cell cycle phases.