A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts

In this study, an efficient method for the synthesis of new cyclophanes (5a–f, 6a–g) through the condensation of 1,4-phenylenedimethanamine (3) or 2,3,5,6-tetramethylbenzene-1,4-diamine (4) with 2-substituted vinamidiniums (2a–g) is described. The cyclophane derivatives are obtained in good to excel...

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Detalles Bibliográficos
Autores principales: Golzar, Nooshin, Mehranpour, Abdolmohammad, Nowrouzi, Najmeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697689/
https://www.ncbi.nlm.nih.gov/pubmed/35423896
http://dx.doi.org/10.1039/d0ra10548a
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author Golzar, Nooshin
Mehranpour, Abdolmohammad
Nowrouzi, Najmeh
author_facet Golzar, Nooshin
Mehranpour, Abdolmohammad
Nowrouzi, Najmeh
author_sort Golzar, Nooshin
collection PubMed
description In this study, an efficient method for the synthesis of new cyclophanes (5a–f, 6a–g) through the condensation of 1,4-phenylenedimethanamine (3) or 2,3,5,6-tetramethylbenzene-1,4-diamine (4) with 2-substituted vinamidiniums (2a–g) is described. The cyclophane derivatives are obtained in good to excellent yields in the presence of acetic acid in refluxing acetonitrile after 15 h. The structure of new compounds was validated based on their spectral data ((1)H NMR, (13)C NMR, IR) and elemental analysis.
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spelling pubmed-86976892022-04-13 A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts Golzar, Nooshin Mehranpour, Abdolmohammad Nowrouzi, Najmeh RSC Adv Chemistry In this study, an efficient method for the synthesis of new cyclophanes (5a–f, 6a–g) through the condensation of 1,4-phenylenedimethanamine (3) or 2,3,5,6-tetramethylbenzene-1,4-diamine (4) with 2-substituted vinamidiniums (2a–g) is described. The cyclophane derivatives are obtained in good to excellent yields in the presence of acetic acid in refluxing acetonitrile after 15 h. The structure of new compounds was validated based on their spectral data ((1)H NMR, (13)C NMR, IR) and elemental analysis. The Royal Society of Chemistry 2021-04-13 /pmc/articles/PMC8697689/ /pubmed/35423896 http://dx.doi.org/10.1039/d0ra10548a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Golzar, Nooshin
Mehranpour, Abdolmohammad
Nowrouzi, Najmeh
A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title_full A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title_fullStr A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title_full_unstemmed A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title_short A facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
title_sort facile and efficient route to one-pot synthesis of new cyclophanes using vinamidinium salts
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697689/
https://www.ncbi.nlm.nih.gov/pubmed/35423896
http://dx.doi.org/10.1039/d0ra10548a
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