Cargando…

Nivolumab‐induced liver injury with a steroid‐refractory increase in biliary enzymes, in a patient with malignant mesothelioma: An autopsy case report

This is the first autopsy report of hepatotoxicity from nivolumab immunotherapy for malignant mesothelioma. The increase in levels of biliary enzymes and randomly distributed endothelial damage were steroid‐refractory, but second‐line option was abandoned because of cachexia. Further discussions are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arai, Kazumori, Matsuda, Masanori, Nakayasu, Hiromasa, Meguro, Shiori, Kurokami, Takafumi, Kubota, Aki, Iwasaki, Tomohiro, Suzuki, Makoto, Kawaguchi, Shinya, Iwashita, Toshihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697699/ https://www.ncbi.nlm.nih.gov/pubmed/34987810 http://dx.doi.org/10.1002/ccr3.5174

Ejemplares similares

An autopsy case of disseminated carcinomatosis of the bone marrow from esophageal adenocarcinoma
por: Suzuki, Daisuke, et al.
Publicado: (2023)

An Autopsy Case of a 5-Year-Old Child with Acute Pancreatitis Caused by Eosinophilic Granulomatosis with Polyangiitis-like Necrotizing Vasculitis
por: Yagi, Haruna, et al.
Publicado: (2019)

An autopsy case of ovarian mucinous cystic tumor complicated by ovarian abscess and a review of the English literature
por: Suzuki, Daisuke, et al.
Publicado: (2022)

Short-Term Biliary Stent Placement Contributing Common Bile Duct Stone Disappearance with Preservation of Duodenal Papilla Function
por: Ueda, Tatsuki, et al.
Publicado: (2016)

Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences
por: Akamatsu, Taisuke, et al.
Publicado: (2013)

An Autopsy Case of Late-onset Fulminant Myocarditis Induced by Nivolumab in Gastric Cancer
por: Naganuma, Ken, et al.
Publicado: (2022)

Remarkable response to nivolumab in sarcomatoid malignant pleural mesothelioma with high PD‐L1
por: Tsubouchi, Kazuya, et al.
Publicado: (2020)

An exceptional response to nivolumab in relapsed and refractory malignant mesothelioma
por: Talreja, Vikas T., et al.
Publicado: (2019)

An autopsy case report of yellow nail syndrome coincided with primary biliary cholangitis
por: Kato, Takafumi, et al.
Publicado: (2020)

Effects of intrapulmonary viral tropism and cytokine expression on the histological patterns of cytomegalovirus pneumonia
por: Arai, Yoshifumi, et al.
Publicado: (2012)

Periostin expression and its supposed roles in benign and malignant thyroid nodules: an immunohistochemical study of 105 cases
por: Kusafuka, Kimihide, et al.
Publicado: (2021)

The NanoSuit method: a novel histological approach for examining paraffin sections in a nondestructive manner by correlative light and electron microscopy
por: Kawasaki, Hideya, et al.
Publicado: (2019)

Efficacy and safety of nivolumab for metastatic biliary tract cancer
por: Gou, Miaomiao, et al.
Publicado: (2019)

Nivolumab-induced immune thrombocytopenia in a patient with malignant pleural mesothelioma
por: Sakakibara-Konishi, Jun, et al.
Publicado: (2020)

Sarcomatoid malignant pleural mesothelioma treated with nivolumab: A case series
por: Hashimoto, Kentaro, et al.
Publicado: (2022)

Gremlin-1 for the Differential Diagnosis of Idiopathic Pulmonary Fibrosis Versus Other Interstitial Lung Diseases: A Clinical and Pathophysiological Analysis
por: Aoshima, Yoichiro, et al.
Publicado: (2021)

Accurate deep learning model using semi-supervised learning and Noisy Student for cervical cancer screening in low magnification images
por: Kurita, Yuki, et al.
Publicado: (2023)

Involvement of Annexin A2 Expression and Apoptosis in Reverse Polarization of Invasive Micropapillary Carcinoma of the Breast
por: Arai, Kazumori, et al.
Publicado: (2020)

Annexin A2 Expression in the Aerogenous Spread of Pulmonary Invasive Mucinous Adenocarcinoma with Gastric Lineage
por: Arai, Kazumori, et al.
Publicado: (2020)

Mediastinal undifferentiated pleomorphic sarcoma with pleural effusion cytopathologically misdiagnosed as epithelial malignant pleural mesothelioma: An autopsy case report
por: Matsumoto, Kinnosuke, et al.
Publicado: (2021)

Aberrant fetal macrophage/microglial reactions to cytomegalovirus infection
por: Sakao-Suzuki, Makiko, et al.
Publicado: (2014)

Phase 2 Trial of Nivolumab and Ramucirumab for Relapsed Mesothelioma: HCRN-LUN15-299
por: Dudek, Arkadiusz Z., et al.
Publicado: (2023)

Immunohistochemical examination using the pericyte marker myosin 1B in a perivascular myoid tumor of soft tissue with definitive pericytic differentiation
por: Meguro, Shiori, et al.
Publicado: (2019)

LTBP2 is secreted from lung myofibroblasts and is a potential biomarker for idiopathic pulmonary fibrosis
por: Enomoto, Yasunori, et al.
Publicado: (2018)

CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes
por: Matsushima, Sayomi, et al.
Publicado: (2020)

Malignant Pleural Mesothelioma with Marked Lymphatic Involvement: A Report of Two Autopsy Cases
por: Ideguchi, Reiko, et al.
Publicado: (2017)

Nasal glomus tumor: A rare nasal tumor with diffuse and strongly positive synaptophysin expression
por: Meguro, Shiori, et al.
Publicado: (2019)

Diagnosis of Ion-Exchange Resin Depositions in Paraffin Sections Using Corrective Light and Electron Microscopy-NanoSuit Method
por: Ooishi, Mako, et al.
Publicado: (2021)

Delayed nivolumab‐induced hepatotoxicity during pazopanib treatment for metastatic renal cell carcinoma: An autopsy case
por: Todo, Maki, et al.
Publicado: (2019)

A randomized phase 2 trial of nivolumab, gemcitabine, and cisplatin or nivolumab and ipilimumab in previously untreated advanced biliary cancer: BilT‐01
por: Sahai, Vaibhav, et al.
Publicado: (2022)

Biliary Atresia in an Infant Presenting With Kabuki Syndrome: An Autopsy Report and Review of the Literature
por: Tralongo, Pietro, et al.
Publicado: (2023)

Nivolumab Immunotherapy in Malignant Mesothelioma: A Case Report Highlighting a New Opportunity for Exceptional Outcomes
por: Jones, Riley G., et al.
Publicado: (2018)

Correlation between immune-related adverse events and therapeutic effects of nivolumab in patients with malignant pleural mesothelioma
por: Yoneda, Hiroto, et al.
Publicado: (2021)

Abdominal pain as an initial symptom of isolated ACTH deficiency induced by nivolumab in a patient with malignant mesothelioma
por: Hata, Koichi, et al.
Publicado: (2021)

A real-world experience of second-line nivolumab in mesothelioma patients during the COVID-19 pandemic
por: Church, Matt, et al.
Publicado: (2021)

Environmental Atlas of Prokaryotes Enables Powerful and Intuitive Habitat-Based Analysis of Community Structures
por: Mise, Kazumori, et al.
Publicado: (2020)

Unexpected absence of ribosomal protein genes from metagenome-assembled genomes
por: Mise, Kazumori, et al.
Publicado: (2022)

Membranous S100A10 involvement in the tumor budding of colorectal cancer during oncogenesis: report of two cases with immunohistochemical analysis
por: Arai, Kazumori, et al.
Publicado: (2020)

Annexin A2 Expression in Aerogenous Metastasis of Pulmonary Invasive Mucinous Adenocarcinoma: A Case Report including Immunohistochemical Analysis
por: Arai, Kazumori, et al.
Publicado: (2019)

New 14-mm diameter Niti-S biliary uncovered metal stent for unresectable distal biliary malignant obstruction
por: Kikuyama, Masataka, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_68gho92t6ahg3upa6kubo2669o