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Exploration of the cofactor specificity of wild-type phosphite dehydrogenase and its mutant using molecular dynamics simulations

Phosphite dehydrogenase (Pdh) catalyzes the NAD-dependent oxidation of phosphite to phosphate with the formation of NADH. It can be used in several bioorthogonal systems for metabolic control and related applications, for example, bioelectricity. At present, NAD has poor stability at high concentrat...

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Detalles Bibliográficos
Autores principales:	Liu, Kunlu, Wang, Min, Zhou, Yubo, Wang, Hongxiang, Liu, Yudong, Han, Lu, Han, Weiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697927/ https://www.ncbi.nlm.nih.gov/pubmed/35424015 http://dx.doi.org/10.1039/d1ra00221j

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