Feline Blood Groups: A Systematic Review of Phylogenetic and Geographical Origin

SIMPLE SUMMARY: Numerous breeds have been identified in the domestic cat, grouped according to their phylogenetic or geographical origin. In the cat, the AB blood group system is the most important feline system, and the determination of the blood group by specific methods is an essential step to avoid or reduce the risk of an adverse reaction in the recipient patient. Many studies have been published on the distribution and prevalence of blood types in pedigree and non-pedigree cats, but the information has never been collated in a systematic manner. ABSTRACT: Domestic cats descended from the African wildcat several thousand years ago. Cats have spread to all parts of the world, probably along routes between civilizations or geographical boundaries, leading to the movement of species, from Asia to the African continent through the Mediterranean basin, and finally to the American continent, Australia, and New Zealand. Currently, 73 cat breeds are recognized by the International Cat Association. With the increasing interest in the selection of breeds, the determination of blood groups in cats has acquired importance over time. The AB blood group system is the most important blood system in cats, in which A, B, and AB or C blood groups are identified. This systematic review describes data from previously published reports about cat blood types and cat breeds. After applying specific criteria, 28 eligible studies were identified in which the prevalence percentages for each blood group in correlation with specific cat breeds were reported. The breeds were, in turn, divided into four groups according to their geographic and phylogenetic origins as follows: Asian cat breeds, American cat breeds, European cat breeds, and breeds from Oceania. Although numerous studies were carried out before 2021, gaps in the literature on the AB system and, in particular, the Mik group are highlighted.