Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte

In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART) deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte maturation and in fertility preservation for women facing the risk of losing fertility. However, to date, it is still n...

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Autores principales: Yang, Huixia, Kolben, Thomas, Meister, Sarah, Paul, Corinna, van Dorp, Julia, Eren, Sibel, Kuhn, Christina, Rahmeh, Martina, Mahner, Sven, Jeschke, Udo, von Schönfeldt, Viktoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698296/
https://www.ncbi.nlm.nih.gov/pubmed/34944731
http://dx.doi.org/10.3390/biomedicines9121904
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author Yang, Huixia
Kolben, Thomas
Meister, Sarah
Paul, Corinna
van Dorp, Julia
Eren, Sibel
Kuhn, Christina
Rahmeh, Martina
Mahner, Sven
Jeschke, Udo
von Schönfeldt, Viktoria
author_facet Yang, Huixia
Kolben, Thomas
Meister, Sarah
Paul, Corinna
van Dorp, Julia
Eren, Sibel
Kuhn, Christina
Rahmeh, Martina
Mahner, Sven
Jeschke, Udo
von Schönfeldt, Viktoria
author_sort Yang, Huixia
collection PubMed
description In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART) deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte maturation and in fertility preservation for women facing the risk of losing fertility. However, to date, it is still not widely used in clinical practice because of its underperformance. The influencing factors, such as biphasic IVM system, culture medium, and the supplementation, have a marked effect on the outcomes of oocyte IVM. However, the role of different culture media, supplements, and follicular priming regimens in oocyte IVM have yet to be fully clarified and deserve further investigation.
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spelling pubmed-86982962021-12-24 Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte Yang, Huixia Kolben, Thomas Meister, Sarah Paul, Corinna van Dorp, Julia Eren, Sibel Kuhn, Christina Rahmeh, Martina Mahner, Sven Jeschke, Udo von Schönfeldt, Viktoria Biomedicines Review In vitro maturation (IVM) of oocytes is a promising assisted reproductive technology (ART) deemed as a simple and safe procedure. It is mainly used in patients with impaired oocyte maturation and in fertility preservation for women facing the risk of losing fertility. However, to date, it is still not widely used in clinical practice because of its underperformance. The influencing factors, such as biphasic IVM system, culture medium, and the supplementation, have a marked effect on the outcomes of oocyte IVM. However, the role of different culture media, supplements, and follicular priming regimens in oocyte IVM have yet to be fully clarified and deserve further investigation. MDPI 2021-12-14 /pmc/articles/PMC8698296/ /pubmed/34944731 http://dx.doi.org/10.3390/biomedicines9121904 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yang, Huixia
Kolben, Thomas
Meister, Sarah
Paul, Corinna
van Dorp, Julia
Eren, Sibel
Kuhn, Christina
Rahmeh, Martina
Mahner, Sven
Jeschke, Udo
von Schönfeldt, Viktoria
Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title_full Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title_fullStr Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title_full_unstemmed Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title_short Factors Influencing the In Vitro Maturation (IVM) of Human Oocyte
title_sort factors influencing the in vitro maturation (ivm) of human oocyte
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698296/
https://www.ncbi.nlm.nih.gov/pubmed/34944731
http://dx.doi.org/10.3390/biomedicines9121904
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