Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole

The rhodium-catalyzed olefination and deuteration of tetrahydrocarbazoles in water with the aid of an N,N-dimethylcarbamoyl-protected group is presented. This olefination method features a broad substrate scope, good functional-group tolerance, and high efficiency in water. Practical applications of...

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Autores principales: Peng, Wan, Liu, Qiaohong, Yin, Fucheng, Shi, Cunjian, Ji, Limei, Qu, Lailiang, Wang, Cheng, Luo, Heng, Kong, Lingyi, Wang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698316/
https://www.ncbi.nlm.nih.gov/pubmed/35423333
http://dx.doi.org/10.1039/d1ra00236h
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author Peng, Wan
Liu, Qiaohong
Yin, Fucheng
Shi, Cunjian
Ji, Limei
Qu, Lailiang
Wang, Cheng
Luo, Heng
Kong, Lingyi
Wang, Xiaobing
author_facet Peng, Wan
Liu, Qiaohong
Yin, Fucheng
Shi, Cunjian
Ji, Limei
Qu, Lailiang
Wang, Cheng
Luo, Heng
Kong, Lingyi
Wang, Xiaobing
author_sort Peng, Wan
collection PubMed
description The rhodium-catalyzed olefination and deuteration of tetrahydrocarbazoles in water with the aid of an N,N-dimethylcarbamoyl-protected group is presented. This olefination method features a broad substrate scope, good functional-group tolerance, and high efficiency in water. Practical applications of the protocol are illustrated by the synthesis of various evodiamine derivatives. As such, this environmentally friendly approach to directly modify natural products will attract much attention in academic and industrial research.
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spelling pubmed-86983162022-04-13 Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole Peng, Wan Liu, Qiaohong Yin, Fucheng Shi, Cunjian Ji, Limei Qu, Lailiang Wang, Cheng Luo, Heng Kong, Lingyi Wang, Xiaobing RSC Adv Chemistry The rhodium-catalyzed olefination and deuteration of tetrahydrocarbazoles in water with the aid of an N,N-dimethylcarbamoyl-protected group is presented. This olefination method features a broad substrate scope, good functional-group tolerance, and high efficiency in water. Practical applications of the protocol are illustrated by the synthesis of various evodiamine derivatives. As such, this environmentally friendly approach to directly modify natural products will attract much attention in academic and industrial research. The Royal Society of Chemistry 2021-02-23 /pmc/articles/PMC8698316/ /pubmed/35423333 http://dx.doi.org/10.1039/d1ra00236h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Peng, Wan
Liu, Qiaohong
Yin, Fucheng
Shi, Cunjian
Ji, Limei
Qu, Lailiang
Wang, Cheng
Luo, Heng
Kong, Lingyi
Wang, Xiaobing
Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title_full Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title_fullStr Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title_full_unstemmed Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title_short Rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
title_sort rhodium(iii) catalyzed olefination and deuteration of tetrahydrocarbazole
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698316/
https://www.ncbi.nlm.nih.gov/pubmed/35423333
http://dx.doi.org/10.1039/d1ra00236h
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