Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice

A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology, including epilepsy and metabolic abnormalities. Disruption of ganglioside production by this enzyme may also have a role in the development of ne...

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Detalles Bibliográficos
Autores principales: Strekalova, Tatyana, Veniaminova, Ekaterina, Svirin, Evgeniy, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W. Y., Proshin, Andrey, Tan, Shawn Zheng Kai, Khairuddin, Sharafuddin, Lim, Lee Wei, Lesch, Klaus-Peter, Walitza, Susanne, Anthony, Daniel C., Ponomarev, Eugene D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698374/
https://www.ncbi.nlm.nih.gov/pubmed/34944404
http://dx.doi.org/10.3390/biom11121759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698374/
https://www.ncbi.nlm.nih.gov/pubmed/34944404
http://dx.doi.org/10.3390/biom11121759

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