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Sex-Specific ADHD-like Behaviour, Altered Metabolic Functions, and Altered EEG Activity in Sialyltransferase ST3GAL5-Deficient Mice
A deficiency in GM3-derived gangliosides, resulting from a lack of lactosylceramide-alpha-2,3-sialyltransferase (ST3GAL5), leads to severe neuropathology, including epilepsy and metabolic abnormalities. Disruption of ganglioside production by this enzyme may also have a role in the development of ne...
Autores principales: | Strekalova, Tatyana, Veniaminova, Ekaterina, Svirin, Evgeniy, Kopeikina, Ekaterina, Veremeyko, Tatyana, Yung, Amanda W. Y., Proshin, Andrey, Tan, Shawn Zheng Kai, Khairuddin, Sharafuddin, Lim, Lee Wei, Lesch, Klaus-Peter, Walitza, Susanne, Anthony, Daniel C., Ponomarev, Eugene D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698374/ https://www.ncbi.nlm.nih.gov/pubmed/34944404 http://dx.doi.org/10.3390/biom11121759 |
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