Cargando…
Reintroduction of DJ-1 in Müller Cells Inhibits Retinal Degeneration in the DJ-1 Deficient Retina
The eye is continuously under oxidative stress due to high metabolic activity and reactive oxygen species generated by daily light exposure. The redox-sensitive protein DJ-1 has proven to be essential in order to protect retina and retinal pigment epithelium (RPE) from oxidative-stress-induced degen...
Autores principales: | Gharbi, Naouel, Røise, Dagne, Førre, Jorunn-Elise, Edson, Amanda J., Hushagen, Helena A., Tronci, Valentina, Frøyset, Ann-Kristin, Fladmark, Kari E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698414/ https://www.ncbi.nlm.nih.gov/pubmed/34942966 http://dx.doi.org/10.3390/antiox10121862 |
Ejemplares similares
-
Astroglial DJ-1 over-expression up-regulates proteins involved in redox regulation and is neuroprotective in vivo
por: Frøyset, Ann Kristin, et al.
Publicado: (2018) -
DJ1 at the interface between neuro-degeneration and cancer
por: Meiser, Johannes, et al.
Publicado: (2017) -
Transcriptional Activation of the Cholecystokinin Gene by DJ-1 through Interaction of DJ-1 with RREB1 and the Effect of DJ-1 on the Cholecystokinin Level in Mice
por: Yamane, Takuya, et al.
Publicado: (2013) -
Monomer DJ-1 and Its N-Terminal Sequence Are Necessary for Mitochondrial Localization of DJ-1 Mutants
por: Maita, Chinatsu, et al.
Publicado: (2013) -
Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1
por: Upadhyay, Mala, et al.
Publicado: (2020)