Cargando…

Overexpression of CERKL Protects Retinal Pigment Epithelium Mitochondria from Oxidative Stress Effects

The precise function of CERKL, a Retinitis Pigmentosa (RP) causative gene, is not yet fully understood. There is evidence that CERKL is involved in the regulation of autophagy, stress granules, and mitochondrial metabolism, and it is considered a gene that is resilient against oxidative stress in th...

Descripción completa

Detalles Bibliográficos
Autores principales:	García-Arroyo, Rocío, Gavaldà-Navarro, Aleix, Villarroya, Francesc, Marfany, Gemma, Mirra, Serena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698444/ https://www.ncbi.nlm.nih.gov/pubmed/34943121 http://dx.doi.org/10.3390/antiox10122018

Ejemplares similares

CERKL, a Retinal Dystrophy Gene, Regulates Mitochondrial Transport and Dynamics in Hippocampal Neurons
por: García-Arroyo, Rocío, et al.
Publicado: (2022)

Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress
por: Tuson, Miquel, et al.
Publicado: (2009)

Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl(KD/KO) mouse model triggers retinal degeneration pathways upon acute light stress
por: García-Arroyo, Rocío, et al.
Publicado: (2023)

A New Cerkl Mouse Model Generated by CRISPR-Cas9 Shows Progressive Retinal Degeneration and Altered Morphological and Electrophysiological Phenotype
por: Domènech, Elena B., et al.
Publicado: (2020)

Ubiquitin Specific Protease USP48 Destabilizes NF-κB/p65 in Retinal Pigment Epithelium Cells
por: Mirra, Serena, et al.
Publicado: (2022)

The Alter Retina: Alternative Splicing of Retinal Genes in Health and Disease
por: Aísa-Marín, Izarbe, et al.
Publicado: (2021)

CERKL Knockdown Causes Retinal Degeneration in Zebrafish
por: Riera, Marina, et al.
Publicado: (2013)

In Vitro Gene Delivery in Retinal Pigment Epithelium Cells by Plasmid DNA-Wrapped Gold Nanoparticles
por: Trigueros, Sònia, et al.
Publicado: (2019)

Mutations in CERKL and RP1 cause retinitis pigmentosa in Pakistani families
por: Nadeem, Raheela, et al.
Publicado: (2020)

SIRT6 overexpression in the nucleus protects mouse retinal pigment epithelium from oxidative stress
por: Yang, Xue, et al.
Publicado: (2023)

Fibroblast growth factor 21 in breast milk controls neonatal intestine function
por: Gavaldà-Navarro, Aleix, et al.
Publicado: (2015)

Antimicrobial promotion of pig growth is associated with tissue-specific remodeling of bile acid signature and signaling
por: Ipharraguerre, Ignacio R., et al.
Publicado: (2018)

Genetic and Clinical Findings in an Ethnically Diverse Cohort with Retinitis Pigmentosa Associated with Pathogenic Variants in CERKL
por: Downes, Susan M., et al.
Publicado: (2020)

Membrane Blue Dual Protects Retinal Pigment Epithelium Cells/Ganglion Cells—Like through Modulation of Mitochondria Function
por: Grossini, Elena, et al.
Publicado: (2022)

Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment
por: Miura, Masahiro, et al.
Publicado: (2019)

Pigment epithelium-derived factor protects retinal ganglion cells
por: Pang, Iok-Hou, et al.
Publicado: (2007)

Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit
por: Zhao, Lian, et al.
Publicado: (2007)

Setting Eyes on the Retinal Pigment Epithelium
por: Moreno-Marmol, Tania, et al.
Publicado: (2018)

Functions and Diseases of the Retinal Pigment Epithelium
por: Yang, Song, et al.
Publicado: (2021)

Paraoxonase Enzyme Protects Retinal Pigment Epithelium from Chlorpyrifos Insult
por: Jasna, Jagan Mohan, et al.
Publicado: (2014)

Retinal Pigment Epithelium and Photoreceptor Preconditioning Protection Requires Docosanoid Signaling
por: Knott, Eric J., et al.
Publicado: (2017)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
por: Zhang, Youwen, et al.
Publicado: (2010)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer
por: Schlanitz, Ferdinand, et al.
Publicado: (2019)

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium
por: Zhu, Zhe, et al.
Publicado: (2022)

CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1
por: Hu, Xuebin, et al.
Publicado: (2018)

Efficacy of various antioxidants in the protection of the retinal pigment epithelium from oxidative stress
por: Kagan, Dov B, et al.
Publicado: (2012)

Antioxidative and Mitochondrial Protection in Retinal Pigment Epithelium: New Light Source in Action
por: Jin, Ming, et al.
Publicado: (2023)

Components of the cytoskeleton in the retinal pigmented epithelium of the chick
Publicado: (1985)

Retinal Pigment Epithelium Derived Stem Cells
por: Hiscott, Paul, et al.
Publicado: (2009)

Characterization of the retinal pigment epithelium in Friedreich ataxia
por: Crombie, Duncan E., et al.
Publicado: (2015)

Retinal pigment epithelium changes in Kartagener syndrome
por: Garcia, Maria D., et al.
Publicado: (2018)

Simple Congenital Hamartoma of the Retinal Pigment Epithelium
por: Nakatsuka, Austin S., et al.
Publicado: (2020)

Circadian Regulation of Retinal Pigment Epithelium Function
por: Baba, Kenkichi, et al.
Publicado: (2022)

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.
por: Bennis, A., et al.
Publicado: (2017)

Reprogramming of the chick retinal pigmented epithelium after retinal injury
por: Luz-Madrigal, Agustin, et al.
Publicado: (2014)

Involvement of the Retinal Pigment Epithelium in the Development of Retinal Lattice Degeneration
por: Mizuno, Hiroshi, et al.
Publicado: (2020)

Shared Features in Retinal Disorders With Involvement of Retinal Pigment Epithelium
por: Sparrow, Janet R., et al.
Publicado: (2021)

Retinal Pigment Epithelium Remodeling in Mouse Models of Retinitis Pigmentosa
por: Napoli, Debora, et al.
Publicado: (2021)

MIND4-17 protects retinal pigment epithelium cells and retinal ganglion cells from UV
por: Li, Chaopeng, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_r0j9ojp6e3sovbi7o36sds8pd5