A Combined Spectroscopic and In Silico Approach to Evaluate the Interaction of Human Frataxin with Mitochondrial Superoxide Dismutase

Frataxin (FXN) is a highly conserved mitochondrial protein whose deficiency causes Friedreich’s ataxia, a neurodegenerative disease. The precise physiological function of FXN is still unclear; however, there is experimental evidence that the protein is involved in biosynthetic iron–sulfur cluster ma...

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Detalles Bibliográficos
Autores principales: Doni, Davide, Meggiolaro, Marta, Santos, Javier, Audran, Gérard, Marque, Sylvain R. A., Costantini, Paola, Bortolus, Marco, Carbonera, Donatella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698469/
https://www.ncbi.nlm.nih.gov/pubmed/34944579
http://dx.doi.org/10.3390/biomedicines9121763

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