Cargando…

SYNE1 Exonic Variant rs9479297 Contributes to Concurrent Hepatocellular and Transitional Cell Carcinoma Double Primary Cancer

Unexpected high risk of synchronous/metachronous hepatocellular carcinoma (HCC) and transitional cell carcinoma (TCC) co-occurrence has been discovered previously. Here, we searched for genetic variation contributing to the co-occurrence of this double primary cancer (DPC). Using targeted exome sequ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chu, Yu-De, Kee, Kwong-Ming, Lin, Wey-Ran, Lai, Ming-Wei, Lu, Sheng-Nan, Chung, Wen-Hung, Pang, See-Tong, Yeh, Chau-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698502/ https://www.ncbi.nlm.nih.gov/pubmed/34944636 http://dx.doi.org/10.3390/biomedicines9121819

Ejemplares similares

EGFR and SYNE2 are associated with p21 expression and SYNE2 variants predict post-operative clinical outcomes in HBV-related hepatocellular carcinoma
por: Han, Chuangye, et al.
Publicado: (2016)

Association of SYNE1 locus with bipolar disorder in Chinese population
por: Li, Wenqiang, et al.
Publicado: (2019)

Cyclin-dependent kinase-associated protein phosphatase is overexpressed in alcohol-related hepatocellular carcinoma and influences xenograft tumor growth
por: LIN, WEY-RAN, et al.
Publicado: (2012)

Pericentrin interacts with KASH domain-containing protein Syne-2
por: Falk, N, et al.
Publicado: (2015)

Identifying SYNE1 Ataxia With Novel Mutations in a Chinese Population
por: Peng, Yun, et al.
Publicado: (2018)

SYNE1 Mutation Is Associated with Increased Tumor Mutation Burden and Immune Cell Infiltration in Ovarian Cancer
por: Harbin, Laura M., et al.
Publicado: (2023)

Syne2b/Nesprin-2 Is Required for Actin Organization and Epithelial Integrity During Epiboly Movement in Zebrafish
por: Li, Yu-Long, et al.
Publicado: (2021)

Heterogeneity in clinical features and disease severity in ataxia-associated SYNE1 mutations
por: Wiethoff, Sarah, et al.
Publicado: (2016)

GALNT14 genotype as a response predictor for concurrent chemoradiotherapy in advanced esophageal squamous cell carcinoma
por: Tsou, Yung-Kuan, et al.
Publicado: (2017)

Expression profile of SYNE3 and bioinformatic analysis of its prognostic value and functions in tumors
por: Liao, Liwei, et al.
Publicado: (2020)

Tremulous spastic ataxia in a patient with a homozygous truncating SYNE1 variant
por: Spagnolo, Francesca, et al.
Publicado: (2023)

A Single Nucleotide Polymorphism rs1010816 Predicts Sorafenib Therapeutic Outcomes in Advanced Hepatocellular Carcinoma
por: Lin, Chih-Lang, et al.
Publicado: (2023)

Synaptic Nuclear Envelope Protein 1 (SYNE 1) Ataxia with Amyotrophic Lateral Sclerosis-like Presentation: A Novel Synaptic Nuclear Envelope Protein 1 (SYNE 1) Gene Deletion Mutation from India
por: Nadaf, Swaleha Nurulla, et al.
Publicado: (2020)

Predicting outcomes for recurrent hepatocellular carcinoma within Milan criteria after complete radiofrequency ablation
por: Chen, Hsin-Yeh, et al.
Publicado: (2020)

Serial changes of clinical parameters in a patient with advanced hepatocellular carcinoma with portal vein thrombosis achieving complete response after treatment with sorafenib
por: Kee, Kwong-Ming, et al.
Publicado: (2014)

A Novel Variant in SYNE4 Confirms its Causative Role in Sensorineural Hearing Loss
por: Masterson, John, et al.
Publicado: (2018)

SYNE1-related autosomal recessive cerebellar ataxia, congenital cerebellar hypoplasia, and cognitive impairment
por: Swan, Lauren, et al.
Publicado: (2018)

SYNE1‐QK1 SNPs, G × G and G × E interactions on the risk of hyperlipidaemia
por: Zheng, Peng‐Fei, et al.
Publicado: (2020)

Lack of a Retinal Phenotype in a Syne-2/Nesprin-2 Knockout Mouse Model
por: Falk, Nathalie, et al.
Publicado: (2019)

Expression and clinical significance of SYNE1 and MAGI2 gene promoter methylation in gastric cancer
por: Qu, Yanjun, et al.
Publicado: (2021)

Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness
por: Taiber, Shahar, et al.
Publicado: (2020)

Plasma phenylalanine and glutamine concentrations correlate with subsequent hepatocellular carcinoma occurrence in liver cirrhosis patients: an exploratory study
por: Liang, Kung-Hao, et al.
Publicado: (2020)

WWOX-rs13338697 genotype predicts therapeutic efficacy of ADI-PEG 20 for patients with advanced hepatocellular carcinoma
por: Chu, Yu-De, et al.
Publicado: (2022)

Plasma interleukin-17 and alpha-fetoprotein combination effectively predicts imminent hepatocellular carcinoma occurrence in liver cirrhotic patients
por: Liang, Kung-Hao, et al.
Publicado: (2021)

GALNT14: An Emerging Marker Capable of Predicting Therapeutic Outcomes in Multiple Cancers
por: Lin, Wey-Ran, et al.
Publicado: (2020)

Eye-tracking-aided characterization of saccades and antisaccades in SYNE1 ataxia patients: a pilot study
por: Szpisjak, Laszlo, et al.
Publicado: (2021)

Impact of an MT-RNR1 Gene Polymorphism on Hepatocellular Carcinoma Progression and Clinical Characteristics
por: Lin, Yang-Hsiang, et al.
Publicado: (2021)

Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function
por: Rathje, Mette, et al.
Publicado: (2019)

Development of SyneBrick Vectors As a Synthetic Biology Platform for Gene Expression in Synechococcus elongatus PCC 7942
por: Kim, Wook Jin, et al.
Publicado: (2017)

A novel SYNE1 gene mutation in a Chinese family of Emery-Dreifuss muscular dystrophy-like
por: Chen, Zuzhi, et al.
Publicado: (2017)

Correction to: Eye-tracking-aided characterization of saccades and antisaccades in SYNE1 ataxia patients: a pilot study
por: Szpisjak, Laszlo, et al.
Publicado: (2021)

Hepatic Clostridium Perfringens Abscess Formation after Radiofrequency Ablation Therapy for Hepatocellular Carcinoma: Report of a Rare Case
por: Wang, Ming-Hung, et al.
Publicado: (2021)

Complex IV subunit 1 defect predicts postoperative survival in hepatocellular carcinoma
por: LE, PUO-HSIEN, et al.
Publicado: (2014)

Modifiable Prognostic Factors of Hepatocellular Carcinoma in Patients with Non-Surgical Treatment
por: Yeh, Jen-Hao, et al.
Publicado: (2015)

Genetic association and gene expression studies suggest that genetic variants in the SYNE1 and TNF genes are related to menstrual migraine
por: Rodriguez-Acevedo, Astrid J, et al.
Publicado: (2014)

A novel frameshift mutation of SYNE1 in a Japanese family with autosomal recessive cerebellar ataxia type 8
por: Yoshinaga, Tsuneaki, et al.
Publicado: (2017)

Biallelic SYNE2 Missense Mutations Leading to Nesprin-2 Giant Hypo-Expression Are Associated with Intellectual Disability and Autism
por: Young, Natalie, et al.
Publicado: (2021)

Case Report: Late-Onset Autosomal Recessive Cerebellar Ataxia Associated With SYNE1 Mutation in a Chinese Family
por: Qian, Nannan, et al.
Publicado: (2022)

Novel Compound Heterozygous Mutations in the SYNE1 Gene in a Taiwanese Family: A Case Report and Literature Review
por: Kuo, Chia-Yan, et al.
Publicado: (2023)

Nomogram to Predict the Long-Term Overall Survival of Early-Stage Hepatocellular Carcinoma after Radiofrequency Ablation
por: Kuo, Yuan-Hung, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i8lcc3q713vhnc61rj1sgbtvb8