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Streptozotocin-Induced Diabetes in a Mouse Model (BALB/c) Is Not an Effective Model for Research on Transplantation Procedures in the Treatment of Type 1 Diabetes

Type 1 diabetes (T1D) is characterized by the destruction of over 90% of the β-cells. C-peptide is a parameter for evaluating T1D. Streptozotocin (STZ) is a standard method of inducing diabetes in animals. Eight protocols describe the administration of STZ in mice; C-peptide levels are not taken int...

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Detalles Bibliográficos
Autores principales: Wszola, Michal, Klak, Marta, Kosowska, Anna, Tymicki, Grzegorz, Berman, Andrzej, Adamiok-Ostrowska, Anna, Olkowska-Truchanowicz, Joanna, Uhrynowska-Tyszkiewicz, Izabela, Kaminski, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698562/
https://www.ncbi.nlm.nih.gov/pubmed/34944607
http://dx.doi.org/10.3390/biomedicines9121790