Cargando…

Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration

Pro-angiogenic and anti-angiogenic peptide hydrogels were evaluated against the standard of care wet age-related macular degeneration (AMD) therapy, Aflibercept (Eylea(®)). AMD was modeled in rats (laser-induced choroidal neovascularization (CNV) model), where the contralateral eye served as the con...

Descripción completa

Detalles Bibliográficos
Autores principales: Acevedo-Jake, Amanda, Shi, Siyu, Siddiqui, Zain, Sanyal, Sreya, Schur, Rebecca, Kaja, Simon, Yuan, Alex, Kumar, Vivek A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698576/
https://www.ncbi.nlm.nih.gov/pubmed/34940343
http://dx.doi.org/10.3390/bioengineering8120190