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Preclinical Efficacy of Pro- and Anti-Angiogenic Peptide Hydrogels to Treat Age-Related Macular Degeneration
Pro-angiogenic and anti-angiogenic peptide hydrogels were evaluated against the standard of care wet age-related macular degeneration (AMD) therapy, Aflibercept (Eylea(®)). AMD was modeled in rats (laser-induced choroidal neovascularization (CNV) model), where the contralateral eye served as the con...
Autores principales: | Acevedo-Jake, Amanda, Shi, Siyu, Siddiqui, Zain, Sanyal, Sreya, Schur, Rebecca, Kaja, Simon, Yuan, Alex, Kumar, Vivek A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698576/ https://www.ncbi.nlm.nih.gov/pubmed/34940343 http://dx.doi.org/10.3390/bioengineering8120190 |
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