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How Localized Z-Disc Damage Affects Force Generation and Gene Expression in Cardiomyocytes

The proper function of cardiomyocytes (CMs) is highly related to the Z-disc, which has a pivotal role in orchestrating the sarcomeric cytoskeletal function. To better understand Z-disc related cardiomyopathies, novel models of Z-disc damage have to be developed. Human pluripotent stem cell (hPSC)-de...

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Detalles Bibliográficos
Autores principales:	Müller, Dominik, Donath, Sören, Brückner, Emanuel Georg, Biswanath Devadas, Santoshi, Daniel, Fiene, Gentemann, Lara, Zweigerdt, Robert, Heisterkamp, Alexander, Kalies, Stefan Michael Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698600/ https://www.ncbi.nlm.nih.gov/pubmed/34940366 http://dx.doi.org/10.3390/bioengineering8120213

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