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Murine Neonatal Oxidant Lung Injury: NRF2-Dependent Predisposition to Adulthood Respiratory Viral Infection and Protection by Maternal Antioxidant

NRF2 protects against oxidant-associated airway disorders via cytoprotective gene induction. To examine if NRF2 is an important determinant of respiratory syncytial virus (RSV) susceptibility after neonate lung injury, Nrf2-deficient (Nrf2(−/−)) and wild-type (Nrf2(+/+)) mice neonatally exposed to h...

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Detalles Bibliográficos
Autores principales: Cho, Hye-Youn, Miller-DeGraff, Laura, Perrow, Ligon A., Gladwell, Wesley, Panduri, Vijayalakshmi, Lih, Fred B., Kleeberger, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698620/
https://www.ncbi.nlm.nih.gov/pubmed/34942977
http://dx.doi.org/10.3390/antiox10121874