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Synergistic Anticancer Effect of Glycolysis and Histone Deacetylases Inhibitors in a Glioblastoma Model

Over the last decade, we have seen tremendous progress in research on 2-deoxy-D-glucose (2-DG) and its analogs. Clinical trials of 2-DG have demonstrated the challenges of using 2-DG as a monotherapy, due to its poor drug-like characteristics, leading researchers to focus on improving its bioavailab...

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Detalles Bibliográficos
Autores principales: Pająk, Beata, Siwiak-Niedbalska, Ewelina, Jaśkiewicz, Anna, Sołtyka, Maja, Zieliński, Rafał, Domoradzki, Tomasz, Fokt, Izabela, Skóra, Stanisław, Priebe, Waldemar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698815/
https://www.ncbi.nlm.nih.gov/pubmed/34944565
http://dx.doi.org/10.3390/biomedicines9121749