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Pardaxin Activates Excessive Mitophagy and Mitochondria-Mediated Apoptosis in Human Ovarian Cancer by Inducing Reactive Oxygen Species

Most ovarian cancer (OC) patients are diagnosed with stage III or higher disease, resulting in a poor prognosis. Currently, paclitaxel combined with carboplatin shows the best treatment outcome for OC. However, no effective drug is available for patients that do not respond to treatment; thus, new d...

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Detalles Bibliográficos
Autores principales: Chen, Yen-Po, Shih, Po-Chang, Feng, Chien-Wei, Wu, Chang-Cheng, Tsui, Kuan-Hao, Lin, You-Hsien, Kuo, Hsiao-Mei, Wen, Zhi-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698909/
https://www.ncbi.nlm.nih.gov/pubmed/34942985
http://dx.doi.org/10.3390/antiox10121883