Anti-Inflammatory Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Pathology in Niemann–Pick Type C Disease

Niemann–Pick type C (NPC) disease is a rare neurovisceral lipid storage disease with progressive neurodegeneration, leading to premature death. The disease is caused by loss-of-function mutations either in the NPC1 or NPC2 gene which results in lipid accumulation in the late endosomes and lysosomes....

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Detalles Bibliográficos
Autores principales: Van Hoecke, Lien, Van Cauwenberghe, Caroline, Börger, Verena, Bruggeman, Arnout, Castelein, Jonas, Van Imschoot, Griet, Van Wonterghem, Elien, Dittrich, Robin, Claeys, Wouter, Xie, Junhua, Giebel, Bernd, Vandenbroucke, Roosmarijn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698931/
https://www.ncbi.nlm.nih.gov/pubmed/34944681
http://dx.doi.org/10.3390/biomedicines9121864

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