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Dissecting the Transcriptomes of Multiple Metronidazole-Resistant and Sensitive Trichomonas vaginalis Strains Identified Distinct Genes and Pathways Associated with Drug Resistance and Cell Death

Trichomonas vaginalis is the causative agent of trichomoniasis, the most prevalent non-viral sexually transmitted infection worldwide. Metronidazole (MTZ) is the mainstay of anti-trichomonal chemotherapy; however, drug resistance has become an increasingly worrying issue. Additionally, the molecular...

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Detalles Bibliográficos
Autores principales: Huang, Po-Jung, Huang, Ching-Yun, Li, Yu-Xuan, Liu, Yi-Chung, Chu, Lichieh-Julie, Yeh, Yuan-Ming, Cheng, Wei-Hung, Chen, Ruei-Ming, Lee, Chi-Ching, Chen, Lih-Chyang, Lin, Hsin-Chung, Chiu, Shu-Fang, Lin, Wei-Ning, Lyu, Ping-Chiang, Tang, Petrus, Huang, Kuo-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698965/
https://www.ncbi.nlm.nih.gov/pubmed/34944632
http://dx.doi.org/10.3390/biomedicines9121817