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Long-Term Effects of Biliverdin Reductase a Deficiency in Ugt1(−/−) Mice: Impact on Redox Status and Metabolism

Accumulation of neurotoxic bilirubin due to a transient neonatal or persistent inherited deficiency of bilirubin glucuronidation activity can cause irreversible brain damage and death. Strategies to inhibit bilirubin production and prevent neurotoxicity in neonatal and adult settings seem promising....

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Detalles Bibliográficos
Autores principales:	Bortolussi, Giulia, Shi, Xiaoxia, ten Bloemendaal, Lysbeth, Banerjee, Bhaswati, De Waart, Dirk R., Baj, Gabriele, Chen, Weiyu, Oude Elferink, Ronald P., Beuers, Ulrich, Paulusma, Coen C., Stocker, Roland, Muro, Andrés F., Bosma, Piter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698966/ https://www.ncbi.nlm.nih.gov/pubmed/34943131 http://dx.doi.org/10.3390/antiox10122029

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