Cargando…
The Pyrazolyl-Urea Gege3 Inhibits the Activity of ANXA1 in the Angiogenesis Induced by the Pancreatic Cancer Derived EVs
The pyrazolyl-urea Gege3 molecule has shown interesting antiangiogenic effects in the tumor contest. Here, we have studied the role of this compound as interfering with endothelial cells activation in response to the paracrine effects of annexin A1 (ANXA1), known to be involved in promoting tumor pr...
Autores principales: | Belvedere, Raffaella, Morretta, Elva, Novizio, Nunzia, Morello, Silvana, Bruno, Olga, Brullo, Chiara, Petrella, Antonello |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699007/ https://www.ncbi.nlm.nih.gov/pubmed/34944403 http://dx.doi.org/10.3390/biom11121758 |
Ejemplares similares
-
Targeting USP-7 by a Novel Fluorinated 5-Pyrazolyl-Urea Derivative
por: Morretta, Elva, et al.
Publicado: (2023) -
ANXA1 Contained in EVs Regulates Macrophage Polarization in Tumor Microenvironment and Promotes Pancreatic Cancer Progression and Metastasis
por: Novizio, Nunzia, et al.
Publicado: (2021) -
The pyrazolyl-urea GeGe3 inhibits tumor angiogenesis and reveals dystrophia myotonica protein kinase (DMPK)1 as a novel angiogenesis target
por: Meta, Elda, et al.
Publicado: (2017) -
Role of Intracellular and Extracellular Annexin A1 in MIA PaCa-2 Spheroids Formation and Drug Sensitivity
por: Novizio, Nunzia, et al.
Publicado: (2022) -
The combination of mesoglycan and VEGF promotes skin wound repair by enhancing the activation of endothelial cells and fibroblasts and their cross-talk
por: Belvedere, Raffaella, et al.
Publicado: (2022)