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RNA Profiling of Mouse Ependymal Cells after Spinal Cord Injury Identifies the Oncostatin Pathway as a Potential Key Regulator of Spinal Cord Stem Cell Fate

Ependymal cells reside in the adult spinal cord and display stem cell properties in vitro. They proliferate after spinal cord injury and produce neurons in lower vertebrates but predominantly astrocytes in mammals. The mechanisms underlying this glial-biased differentiation remain ill-defined. We ad...

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Detalles Bibliográficos
Autores principales: Chevreau, Robert, Ghazale, Hussein, Ripoll, Chantal, Chalfouh, Chaima, Delarue, Quentin, Hemonnot-Girard, Anne Laure, Mamaeva, Daria, Hirbec, Helene, Rothhut, Bernard, Wahane, Shalaka, Perrin, Florence Evelyne, Noristani, Harun Najib, Guerout, Nicolas, Hugnot, Jean Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699053/
https://www.ncbi.nlm.nih.gov/pubmed/34943841
http://dx.doi.org/10.3390/cells10123332