Anticancer Activity of Ω-6 Fatty Acids through Increased 4-HNE in Breast Cancer Cells

SIMPLE SUMMARY: Epidemiological evidence suggests that breast cancer risk is lowered by Ω-3 and increased by Ω-6 polyunsaturated fatty acids (PUFAs). Paradoxically, the Ω-6 PUFA metabolite 4-hydroxynonenal (4-HNE) inhibits cancer cell growth. This duality prompted us to study whether arachidonic aci...

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Detalles Bibliográficos
Autores principales: Bose, Chhanda, Hindle, Ashly, Lee, Jihyun, Kopel, Jonathan, Tonk, Sahil, Palade, Philip T., Singhal, Sharad S., Awasthi, Sanjay, Singh, Sharda P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699056/
https://www.ncbi.nlm.nih.gov/pubmed/34944997
http://dx.doi.org/10.3390/cancers13246377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699056/
https://www.ncbi.nlm.nih.gov/pubmed/34944997
http://dx.doi.org/10.3390/cancers13246377

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