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Therapeutic Targeting of Exportin-1 in Childhood Cancer

SIMPLE SUMMARY: Exportin-1 is a nuclear transport protein that is overexpressed in cancer cells and associated with inferior outcomes across a range of malignancies. Selinexor is a novel FDA-approved inhibitor of Exportin-1 (XPO1). Although significant research has focused on integration of selinexo...

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Detalles Bibliográficos
Autores principales:	Galinski, Basia, Alexander, Thomas B., Mitchell, Daniel A., Chatwin, Hannah V., Awah, Chidiebere, Green, Adam L., Weiser, Daniel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699059/ https://www.ncbi.nlm.nih.gov/pubmed/34944778 http://dx.doi.org/10.3390/cancers13246161

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