β-Hydroxy-β-Methylbutyrate Supplementation Promotes Antitumor Immunity in an Obesity Responsive Mouse Model of Pancreatic Ductal Adenocarcinoma

SIMPLE SUMMARY: Pancreatic cancer (PDAC) is a deadly disease, exacerbated by obesity, which lacks effective therapeutic interventions. Most PDAC has a limited response to immune- and chemotherapy. Treating PDAC is made additionally challenging by the rapid emergence of muscle wasting and cachexia, w...

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Detalles Bibliográficos
Autores principales: Coleman, Michael F., Liu, Kristyn A., Pfeil, Alexander J., Etigunta, Suhas K., Tang, Xiaohu, Fabela, Salvador, Lashinger, Laura M., Cui, Zhengrong, Hursting, Stephen D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699071/
https://www.ncbi.nlm.nih.gov/pubmed/34944981
http://dx.doi.org/10.3390/cancers13246359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699071/
https://www.ncbi.nlm.nih.gov/pubmed/34944981
http://dx.doi.org/10.3390/cancers13246359

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