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Benefits and Toxicity of Disulfiram in Preclinical Models of Nephropathic Cystinosis

Nephropathic cystinosis is a rare disease caused by mutations of the CTNS gene that encodes for cystinosin, a lysosomal cystine/H+ symporter. The disease is characterized by early-onset chronic kidney failure and progressive development of extra-renal complications related to cystine accumulation in...

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Detalles Bibliográficos
Autores principales:	Taranta, Anna, Elmonem, Mohamed A., Bellomo, Francesco, De Leo, Ester, Boenzi, Sara, Janssen, Manoe J., Jamalpoor, Amer, Cairoli, Sara, Pastore, Anna, De Stefanis, Cristiano, Colucci, Manuela, Rega, Laura R., Giovannoni, Isabella, Francalanci, Paola, van den Heuvel, Lambertus P., Dionisi-Vici, Carlo, Goffredo, Bianca M., Masereeuw, Rosalinde, Levtchenko, Elena, Emma, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699074/ https://www.ncbi.nlm.nih.gov/pubmed/34943802 http://dx.doi.org/10.3390/cells10123294

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