Cargando…
Mitochondrial Bioenergetic and Proteomic Phenotyping Reveals Organ-Specific Consequences of Chronic Kidney Disease in Mice
Chronic kidney disease (CKD) results in reduced kidney function, uremia, and accumulation of uremic metabolites. Mitochondrial alterations have been suggested to play a role in the disease pathology within various tissues. The purpose of this study was to perform a comprehensive bioenergetic and pro...
Autores principales: | Thome, Trace, Coleman, Madeline D., Ryan, Terence E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699079/ https://www.ncbi.nlm.nih.gov/pubmed/34943790 http://dx.doi.org/10.3390/cells10123282 |
Ejemplares similares
-
Tissue-Specific (1)H-NMR Metabolomic Profiling in Mice with Adenine-Induced Chronic Kidney Disease
por: Khattri, Ram B., et al.
Publicado: (2021) -
Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics
por: Berru, Fabian N., et al.
Publicado: (2019) -
Bioenergetics Consequences of Mitochondrial Transplantation in Cardiomyocytes
por: Ali Pour, Paria, et al.
Publicado: (2020) -
Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease
por: Thome, Trace, et al.
Publicado: (2020) -
Subcellular proteomics combined with bioenergetic phenotyping reveals protein biomarkers of respiratory insufficiency in the setting of proofreading-deficient mitochondrial polymerase
por: McLaughlin, Kelsey L., et al.
Publicado: (2020)