Disruption of Her2-Induced PD-L1 Inhibits Tumor Cell Immune Evasion in Patient-Derived Gastric Cancer Organoids

SIMPLE SUMMARY: HER2 may contribute to immune evasion in gastric cancer that is associated with PD-L1 expression. Autologous organoid/immune cell co-cultures serve as an appropriate in vitro model to study the effects of anti-HER2 targeted therapy in combination with anti-PD1 immune checkpoint inhib...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Jayati, Koh, Vivien, Steele, Nina, Hawkins, Jennifer, Ito, Yoshiaki, Merchant, Juanita L., Wang, Jiang, Helmrath, Michael A., Ahmad, Syed A, So, Jimmy Bok Yan, Yong, Wei Peng, Zavros, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699100/
https://www.ncbi.nlm.nih.gov/pubmed/34944780
http://dx.doi.org/10.3390/cancers13246158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699100/
https://www.ncbi.nlm.nih.gov/pubmed/34944780
http://dx.doi.org/10.3390/cancers13246158

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