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Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?

SIMPLE SUMMARY: The disaccharide lactose is a common excipient in pharmaceutical products. In addition, the two anomers α- and β-lactose can exert immuno-modulatory effects. α-Lactose functions as a major regulator of the T-cell immunoglobulin mucin-3 (Tim-3)/Galectin-9 (Gal-9) immune checkpoint, th...

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Detalles Bibliográficos
Autores principales:	Bailly, Christian, Thuru, Xavier, Quesnel, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699133/ https://www.ncbi.nlm.nih.gov/pubmed/34944985 http://dx.doi.org/10.3390/cancers13246365

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