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Scalable Enrichment of Immunomodulatory Human Acute Myeloid Leukemia Cell Line-Derived Extracellular Vesicles

Acute myeloid leukemia (AML) cells can secrete trophic factors, including extracellular vesicles (EVs), instructing the stromal leukemic niche. Here, we introduce a scalable workflow for purification of immunomodulatory AML-EVs to compare their phenotype and function to the parental AML cells and th...

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Detalles Bibliográficos
Autores principales: Binder, Heide-Marie, Maeding, Nicole, Wolf, Martin, Cronemberger Andrade, André, Vari, Balazs, Krisch, Linda, Gomes, Fausto Gueths, Blöchl, Constantin, Muigg, Katharina, Poupardin, Rodolphe, Raninger, Anna M., Heuser, Thomas, Obermayer, Astrid, Ebner-Peking, Patricia, Pleyer, Lisa, Greil, Richard, Huber, Christian G., Schallmoser, Katharina, Strunk, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699161/
https://www.ncbi.nlm.nih.gov/pubmed/34943829
http://dx.doi.org/10.3390/cells10123321

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