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Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes

The eutrophication of lakes and rivers without adequate rainfall leads to excessive growth of cyanobacterial harmful algal blooms (CyanoHABs) that produce toxicants, green tides, and unpleasant odors. The rapid growth of CyanoHABs owing to global warming, climate change, and the development of rainf...

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Autores principales: Park, Hanbin, Kim, Gahyeon, Seo, Yoseph, Yoon, Yejin, Min, Junhong, Park, Chulhwan, Lee, Taek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699174/
https://www.ncbi.nlm.nih.gov/pubmed/34940282
http://dx.doi.org/10.3390/bios11120525
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author Park, Hanbin
Kim, Gahyeon
Seo, Yoseph
Yoon, Yejin
Min, Junhong
Park, Chulhwan
Lee, Taek
author_facet Park, Hanbin
Kim, Gahyeon
Seo, Yoseph
Yoon, Yejin
Min, Junhong
Park, Chulhwan
Lee, Taek
author_sort Park, Hanbin
collection PubMed
description The eutrophication of lakes and rivers without adequate rainfall leads to excessive growth of cyanobacterial harmful algal blooms (CyanoHABs) that produce toxicants, green tides, and unpleasant odors. The rapid growth of CyanoHABs owing to global warming, climate change, and the development of rainforests and dams without considering the environmental concern towards lakes and rivers is a serious issue. Humans and livestock consuming the toxicant-contaminated water that originated from CyanoHABs suffer severe health problems. Among the various toxicants produced by CyanoHABs, microcystins (MCs) are the most harmful. Excess accumulation of MC within living organisms can result in liver failure and hepatocirrhosis, eventually leading to death. Therefore, it is essential to precisely detect MCs in water samples. To date, the liquid chromatography–mass spectrometry (LC–MS) and enzyme-linked immunosorbent assay (ELISA) have been the standard methods for the detection of MC and provide precise results with high reliability. However, these methods require heavy instruments and complicated operation steps that could hamper the portability and field-readiness of the detection system. Therefore, in order for this goal to be achieved, the biosensor has been attracted to a powerful alternative for MC detection. Thus far, several types of MC biosensor have been proposed to detect MC in freshwater sample. The introduction of material is a useful option in order to improve the biosensor performance and construct new types of biosensors. Introducing nanomaterials to the biosensor interface provides new phenomena or enhances the sensitivity. In recent times, different types of nanomaterials, such as metallic, carbon-based, and transition metal dichalcogenide-based nanomaterials, have been developed and used to fabricate biosensors for MC detection. This study reviews the recent advancements in different nanomaterial-based MC biosensors.
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spelling pubmed-86991742021-12-24 Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes Park, Hanbin Kim, Gahyeon Seo, Yoseph Yoon, Yejin Min, Junhong Park, Chulhwan Lee, Taek Biosensors (Basel) Review The eutrophication of lakes and rivers without adequate rainfall leads to excessive growth of cyanobacterial harmful algal blooms (CyanoHABs) that produce toxicants, green tides, and unpleasant odors. The rapid growth of CyanoHABs owing to global warming, climate change, and the development of rainforests and dams without considering the environmental concern towards lakes and rivers is a serious issue. Humans and livestock consuming the toxicant-contaminated water that originated from CyanoHABs suffer severe health problems. Among the various toxicants produced by CyanoHABs, microcystins (MCs) are the most harmful. Excess accumulation of MC within living organisms can result in liver failure and hepatocirrhosis, eventually leading to death. Therefore, it is essential to precisely detect MCs in water samples. To date, the liquid chromatography–mass spectrometry (LC–MS) and enzyme-linked immunosorbent assay (ELISA) have been the standard methods for the detection of MC and provide precise results with high reliability. However, these methods require heavy instruments and complicated operation steps that could hamper the portability and field-readiness of the detection system. Therefore, in order for this goal to be achieved, the biosensor has been attracted to a powerful alternative for MC detection. Thus far, several types of MC biosensor have been proposed to detect MC in freshwater sample. The introduction of material is a useful option in order to improve the biosensor performance and construct new types of biosensors. Introducing nanomaterials to the biosensor interface provides new phenomena or enhances the sensitivity. In recent times, different types of nanomaterials, such as metallic, carbon-based, and transition metal dichalcogenide-based nanomaterials, have been developed and used to fabricate biosensors for MC detection. This study reviews the recent advancements in different nanomaterial-based MC biosensors. MDPI 2021-12-20 /pmc/articles/PMC8699174/ /pubmed/34940282 http://dx.doi.org/10.3390/bios11120525 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Park, Hanbin
Kim, Gahyeon
Seo, Yoseph
Yoon, Yejin
Min, Junhong
Park, Chulhwan
Lee, Taek
Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title_full Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title_fullStr Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title_full_unstemmed Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title_short Improving Biosensors by the Use of Different Nanomaterials: Case Study with Microcystins as Target Analytes
title_sort improving biosensors by the use of different nanomaterials: case study with microcystins as target analytes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699174/
https://www.ncbi.nlm.nih.gov/pubmed/34940282
http://dx.doi.org/10.3390/bios11120525
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