Differential Expression of Polyamine Pathways in Human Pancreatic Tumor Progression and Effects of Polyamine Blockade on Tumor Microenvironment

SIMPLE SUMMARY: Pancreatic cancer has a five-year survival rate of less than 8% and is the fourth leading cause of cancer death in the United States. Existing therapeutics have failed to improve pancreatic ductal adenocarcinoma (PDAC) patient outcomes. There has been success with other tumor types i...

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Detalles Bibliográficos
Autores principales: Nakkina, Sai Preethi, Gitto, Sarah B., Pandey, Veethika, Parikh, Jignesh G., Geerts, Dirk, Maurer, Hans Carlo, Olive, Kenneth P., Phanstiel, Otto, Altomare, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699198/
https://www.ncbi.nlm.nih.gov/pubmed/34945011
http://dx.doi.org/10.3390/cancers13246391

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