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Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation
Alcohol consumption and obesity are known risk factors of steatohepatitis. Here, we report that the deficiency of CRAMP (cathelicidin-related antimicrobial peptide—gene name: Camp) is protective against a high-fat diet (HFD) plus acute alcohol (HFDE)-induced liver injury. HFDE markedly induced liver...
Autores principales: | Li, Fengyuan, Chen, Jenny, Liu, Yunhuan, Gu, Zelin, Jiang, Mengwei, Zhang, Lihua, Chen, Shao-Yu, Deng, Zhongbin, McClain, Craig J., Feng, Wenke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699208/ https://www.ncbi.nlm.nih.gov/pubmed/34943840 http://dx.doi.org/10.3390/cells10123333 |
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