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The Cross Marks the Spot: The Emerging Role of JmjC Domain-Containing Proteins in Myeloid Malignancies

Histone methylation tightly regulates chromatin accessibility, transcription, proliferation, and cell differentiation, and its perturbation contributes to oncogenic reprogramming of cells. In particular, many myeloid malignancies show evidence of epigenetic dysregulation. Jumonji C (JmjC) domain-con...

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Detalles Bibliográficos
Autores principales: Staehle, Hans Felix, Pahl, Heike Luise, Jutzi, Jonas Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699298/
https://www.ncbi.nlm.nih.gov/pubmed/34944554
http://dx.doi.org/10.3390/biom11121911