Modulation of Hippocampal Astroglial Activity by Synaptamide in Rats with Neuropathic Pain

The present study demonstrates that synaptamide (N-docosahexaenoylethanolamine), an endogenous metabolite of docosahexaenoic acid, when administered subcutaneously (4 mg/kg/day, 14 days), exhibits analgesic activity and promotes cognitive recovery in the rat sciatic nerve chronic constriction injury...

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Detalles Bibliográficos
Autores principales: Manzhulo, Igor, Manzhulo, Olga, Tyrtyshnaia, Anna, Ponomarenko, Arina, Konovalova, Sophia, Ermolenko, Ekaterina, Milkina, Elena, Starinets, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699312/
https://www.ncbi.nlm.nih.gov/pubmed/34942863
http://dx.doi.org/10.3390/brainsci11121561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699312/
https://www.ncbi.nlm.nih.gov/pubmed/34942863
http://dx.doi.org/10.3390/brainsci11121561

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