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Targeting CAMKK2 and SOC Channels as a Novel Therapeutic Approach for Sensitizing Acute Promyelocytic Leukemia Cells to All-Trans Retinoic Acid

Calcium ions (Ca(2+)) play important and diverse roles in the regulation of autophagy, cell death and differentiation. Here, we investigated the impact of Ca(2+) in regulating acute promyelocytic leukemia (APL) cell fate in response to the anti-cancer agent all-trans retinoic acid (ATRA). We observe...

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Detalles Bibliográficos
Autores principales: Merhi, Faten, Alvarez-Valadez, Karla, Trepiana, Jenifer, Lescoat, Claire, Groppi, Alexis, Dupuy, Jean-William, Soubeyran, Pierre, Kroemer, Guido, Vacher, Pierre, Djavaheri-Mergny, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699360/
https://www.ncbi.nlm.nih.gov/pubmed/34943872
http://dx.doi.org/10.3390/cells10123364

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