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Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma

SIMPLE SUMMARY: We aimed at characterizing microRNAs activated downstream of MUC4-associated signaling in pancreatic adenocarcinoma. We investigated the MUC4-miR-210-3p reciprocal regulation and deciphered miR-210-3p biological roles in vitro and in vivo. We showed a MUC4-miR-210-3p negative feedbac...

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Detalles Bibliográficos
Autores principales: Boukrout, Nihad, Souidi, Mouloud, Lahdaoui, Fatima, Duchêne, Belinda, Neve, Bernadette, Coppin, Lucie, Leteurtre, Emmanuelle, Torrisani, Jérôme, Van Seuningen, Isabelle, Jonckheere, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699468/
https://www.ncbi.nlm.nih.gov/pubmed/34944818
http://dx.doi.org/10.3390/cancers13246197

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